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PathAI › Engineering

Senior/Staff Site Reliability Engineer - Data Center

PathAI · Boston (preferred) / Indianapolis

Pay
$146K–$225K
From the posting
Posted
Aug 11, 2026
Tracked open for 77 days
Team
Engineering
Full-time
PathAI hiring
15 open roles
9 in engineering

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Typical infrastructure engineer pay at startups: $213K median, middle half $185K–$256K (207 posted ranges).

Typical engineering pay at PathAI: $128K–$196K — median of 9 listed ranges.

Across all startups we track: $170K–$242K for engineering roles (8,053 listed ranges).

About the role

PathAI's mission is to improve patient outcomes with AI-powered pathology. 

PathAI is transforming traditional pathology methods into powerful, new technologies. These innovations in pathology can help accelerate drug development, improve confidence in the accuracy of diagnosis, and get life-saving therapies to patients more quickly. At PathAI, you'll work with a diverse and talented team of people, who are dedicated to solving complex problems and making a huge impact. 

We are expanding our team and recruiting for a skilled Senior/Staff Site Reliability Engineer focused on designing, building, and operating our on-prem/cloud environment.

The Opportunity

  • You will advance the state of our operations by implementing SRE best practices - focusing on users, monitoring, and automation.
  • You will design, build and operate our data center to support our rapidly growing Machine Learning team.
  • You will build highly-secure on-premises environments handling NIST/ISO standards.
  • You will integrate on-premises datacenter environments with existing cloud infrastructure to create a seamless hybrid cloud environment.
  • You will improve the reliability and resilience of our infrastructure through root-cause analysis and reviewing gaps in designs, and implementations of our infrastructure.
  • You will participate in platform on-call rotations and assist with urgent incident response.

Who You Are:
(Required)

  • You have a BS in Computer Science, Computer Engineering, Electrical Engineering, Software Engineering or closely related technical field.
  • You have 8 years experience working in physical hardware/facilities, networking, automation or other relevant areas.
  • You have demonstrated experience with modern datacenter network designs and comfort operating across network layers.
  • You’ve administered physical hardware stacks in production settings (iDRAC/IPMI/Nvidia UFM/Juniper Systems).
  • You have demonstrated experience and opinions on virtualization, containerization, or container orchestration platforms. (EKS-Anywhere/ClusterAPI/KVM).
  • You have strong expertise in storage solutions and optimizing them for high-performance workloads (e.g., Quobyte, S3, FSx, EFS).
  • You are highly proficient with automation tools; you eliminate toil by automating everything through scripting, configuration management tools (Ansible/RedFish).
  • You’ve built monitoring infrastructure with modern observability tools (Datadog/Grafana/Prometheus).
  • You have a proven operational background managing critical production systems, with extensive experience in incident response, infrastructure scaling, and navigating high-growth challenges.
  • You have the ability to travel to onsite Datacenter location(s) as needed.

Preferred:

  • You have outstanding interpersonal, verbal, and written communication and influencing skills: have built and cultivated important relationships both inside and outside of the organization and externally; have proven abilities to influence internal partners and stakeholders, thought leaders, national advocacy  organizations, national standard-setting bodies, and other relevant external parties.
  • You have strong analytical and critical thinking skills with attention to detail; you have the ability to manage multiple projects and drive results in a fast-paced environment; you have a collaborative mindset with demonstrated leadership capabilities..

This is a hybrid position based in Boston (preferred), NYC, Indianapolis. (A remote option may be considered for an exceptional candidate.)
Relocation benefits are not available for this position.

The expected salary range for this position based on the primary location Boston, MA is $146,250 - $225,000.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  

PathAI is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

From PathAI's careers page. First seen Aug 11, 2026, last verified Oct 28, 2026.

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